The LL-37 Peptide Acne Face Mask is a microbiome-safe clarifying treatment engineered to target active breakouts, congestion, and blemish-prone skin without disrupting your skin's natural bacterial balance. This professional-grade mask delivers antimicrobial peptide LL-37 alongside salicylic acid and niacinamide through an occlusive microfiber matrix—calming inflammation, balancing oil production, and refining pores in just 20 minutes.

LL-37 (Cathelicidin) is a naturally occurring antimicrobial peptide that your immune system produces to fight bacterial infections. Unlike harsh antibiotics or benzoyl peroxide that kill both good and bad bacteria, LL-37 selectively targets acne-causing bacteria (C. acnes) while preserving beneficial skin flora. This makes it ideal for sensitive-acne skin that reacts poorly to traditional acne treatments.

LL-37 also possesses powerful anti-inflammatory properties, reducing the redness and swelling associated with cystic acne and inflammatory breakouts. It works by modulating immune responses and inhibiting pro-inflammatory cytokines, calming active blemishes without the irritation or dryness caused by conventional spot treatments.

Salicylic Acid (BHA) penetrates deep into pores to dissolve sebum plugs and dead skin cells, preventing new breakouts from forming. Niacinamide regulates oil production, reduces pore appearance, and fades post-acne marks by inhibiting melanin transfer. Together, these ingredients create a comprehensive acne-fighting protocol that addresses congestion, active inflammation, and post-breakout scarring.

This mask is ideal for acne-prone skin, hormonal breakouts, congested pores, or anyone seeking a gentler alternative to harsh acne medications. Use 2-3 times weekly for prevention, or apply to specific breakout zones as a targeted treatment during active flare-ups.

ProGlow Tip:
Apply this mask after gentle exfoliation to maximize pore penetration. For stubborn cystic acne, leave the mask on for 30-40 minutes or use as an overnight spot treatment on problem areas.

LL-37 (Cathelicidin Antimicrobial Peptide), Salicylic Acid (BHA), Niacinamide (Vitamin B3), Zinc PCA, Tea Tree Oil

Cleanse your face thoroughly and pat dry. Remove the mask from packaging and unfold carefully. Apply the microfiber mask to your face, ensuring full contact with congested or breakout-prone areas (forehead, nose, chin, cheeks). Leave on for 20-30 minutes. For active cystic acne, leave on for up to 40 minutes or cut mask into smaller sections for targeted spot treatment. Remove and discard. Gently massage remaining serum into skin—do not rinse. Follow with a lightweight, oil-free moisturizer.

Frequency: Use 2-3 times per week for acne prevention and pore refinement. Can be used daily during active breakout periods.

Storage: Store in a cool, dry place. Refrigerate for enhanced soothing on inflamed, cystic acne.

Note: Safe for sensitive, acne-prone skin. LL-37 is microbiome-friendly and does not cause the dryness or irritation associated with benzoyl peroxide or harsh antibiotics. Suitable for hormonal acne, cystic acne, and congested skin. Patch test if you have extremely reactive skin.

Selectively targets acne-causing bacteria without disrupting skin flora.
LL-37 exhibits antimicrobial activity against C. acnes (acne bacteria) while preserving beneficial microbiome balance, preventing the dysbiosis that worsens breakouts.

Reduces inflammation and calms active breakouts.
LL-37 modulates inflammatory cytokines (IL-8, TNF-α) and inhibits NF-κB signaling, visibly reducing redness and swelling in cystic and inflammatory acne.

Unclogs pores and prevents future breakouts.
Salicylic Acid penetrates sebum-filled pores to dissolve buildup, while Zinc PCA regulates oil production to prevent new comedones from forming.

Fades post-acne marks and refines skin texture.
Niacinamide inhibits melanin transfer to reduce post-inflammatory hyperpigmentation, while LL-37's tissue-repair properties accelerate healing and minimize scarring.

Peptide Mechanisms

LL-37 disrupts bacterial cell membranes through electrostatic interactions, selectively targeting pathogenic bacteria while sparing commensal flora. It also modulates Toll-like receptors (TLRs) and inhibits pro-inflammatory cytokine release, reducing inflammation at the cellular level. Salicylic Acid acts as a keratolytic agent, breaking down desmosomes to dissolve dead skin cells and sebum plugs. Niacinamide inhibits melanosome transfer from melanocytes to keratinocytes, reducing post-inflammatory hyperpigmentation. Zinc PCA regulates sebaceous gland activity by inhibiting 5α-reductase, the enzyme that converts testosterone to DHT (a key trigger of excess oil production).